While the theory of belief change has attracted a lot of interest from researchers, work on implementing belief change and actually putting it to use in real-world problems is still scarce. In this paper, we present an implementation of propositional belief change using Binary Decision Diagrams. Upper complexity bounds for the algorithm are presented and discussed. The approach is presented both in the general case, as well as on specific belief change operators from the literature. In an effort to gain (...) a better understanding of the empirical efficiency of the algorithms involved, a fault diagnosis problem on combinational circuits is presented, implemented and evaluated. (shrink)

The literature on affective determinants of physical activity is growing rapidly. The present paper aims to provide greater clarity regarding the definition and distinctions among the various affect-related constructs that have been examined in relation to PA. Affective constructs are organized according to the Affect and Health Behavior Framework, including: affective response to PA; incidental affect; affect processing; and affectively charged motivational states. After defining each category of affective construct, we provide examples of relevant research showing how each construct may (...) relate to PA behavior. We conclude each section with a discussion of future directions for research. (shrink)

Background While prenatal surgery historically was performed exclusively for lethal conditions, today intrauterine surgery is also performed to decrease postnatal disabilities for non-lethal conditions. We sought to describe physicians' attitudes about prenatal surgery for lethal and non-lethal conditions and to elucidate characteristics associated with these attitudes. Methods Survey of 1200 paediatric surgeons, neonatologists and maternal–fetal medicine specialists. Results Of 1176 eligible physicians, 670 responded. In the setting of a lethal condition for which prenatal surgery would likely result in the child (...) surviving with a severe disability, most respondents either disagreed or strongly disagreed that they would recommend the surgery. Male physicians were twice as likely to recommend surgery for the lethal condition, as were physicians who believe that abortion is morally wrong. Older physicians were less likely to recommend surgery. For non-lethal conditions, most respondents agreed that they would recommend prenatal surgery, even if the surgery increases the risk of prematurity or fetal death. Compared with MFMs, surgeons were less likely to recommend such surgery, as were physicians not affiliated with a fetal centre, and physicians who were religious. Conclusion Physician’s attitudes about prenatal surgery relate to physicians’ beliefs about disability as well as demographic, cultural and religious characteristics. Given the variety of views, parents are likely to receive different recommendations from their doctors about the preferable treatment choice. (shrink)

Multimodal integration is the formation of a coherent percept from different sensory inputs such as vision, audition, and somatosensation. Most research on multimodal integration in speech perception has focused on audio-visual integration. In recent years, audio-tactile integration has also been investigated, and it has been established that puffs of air applied to the skin and timed with listening tasks shift the perception of voicing by naive listeners. The current study has replicated and extended these findings by testing the effect of (...) air puffs on gradations of voice onset time along a continuum rather than the voiced and voiceless endpoints of the original work. Three continua were tested: bilabial (“pa/ba”), velar (“ka/ga”), and a vowel continuum (“head/hid”) used as a control. The presence of air puffs was found to significantly increase the likelihood of choosing voiceless responses for the two VOT continua but had no effect on choices for the vowel continuum. Analysis of response times revealed that the presence of air puffs lengthened responses for intermediate (ambiguous) stimuli and shortened them for endpoint (non-ambiguous) stimuli. The slowest response times were observed for the intermediate steps for all three continua, but for the bilabial continuum this effect interacted with the presence of air puffs: responses were slower in the presence of air puffs, and faster in their absence. This suggests that during integration auditory and aero-tactile inputs are weighted differently by the perceptual system, with the latter exerting greater influence in those cases where the auditory cues for voicing are ambiguous. (shrink)

Progressive supranuclear palsy is a movement disorder with prominent tau neuropathology. Brain diseases with abnormal tau deposits are called tauopathies, the most common of which is Alzheimer's disease. Environmental causes of tauopathies include repetitive head trauma associated with some sports. To identify common genetic variation contributing to risk for tauopathies, we carried out a genome-wide association study of 1,114 individuals with PSP and 3,247 controls followed by a second stage in which we genotyped 1,051 cases and 3,560 controls for the (...) stage 1 SNPs that yielded P ≤ 10-3. We found significant previously unidentified signals associated with PSP risk at STX6, EIF2AK3 and MOBP. We confirmed two independent variants in MAPT affecting risk for PSP, one of which influences MAPT brain expression. The genes implicated encode proteins for vesicle-membrane fusion at the Golgi-endosomal interface, for the endoplasmic reticulum unfolded protein response and for a myelin structural component. © 2011 Nature America, Inc. All rights reserved. (shrink)

Our world is a world of change. Children are born and grow into adults. Material possessions rust and decay with age and ultimately perish. Yet scepticism about change is as old as philosophy itself. Heraclitus, for example, argued that nothing could survive the replacement of parts, so that it is impossible to step into the same river twice. Zeno argued that motion is paradoxical, so that nothing can alter its location. Parmenides and his followers went even further, arguing that the (...) very concept of qualitative change is inconsistent. Change in any respect is impossible, they argued, as change requires difference and nothing differs from itself. Few today would accept the Eleatic conclusion that change is impossible. But the topic of change continues to be a source of much debate, as it brings together various issues that are central to metaphysics, language, and logic – including identity, persistence, time, tense, and temporal logic. Author Recommends Wasserman, Ryan. 'The Problem of Change.' Philosophy Compass 1 (2006): 1–10. This article presents the problem of change and provides a brief survey of potential solutions. Haslanger, Sally. 'Persistence Through Time.' The Oxford Handbook of Metaphysics . Eds. M. Loux and D. Zimmerman. Oxford: Oxford University Press, 2003. This article presents the problem of change and provides a detailed survey of potential solutions. Heller, Mark. 'Things Change.' Philosophy and Phenomenological Research 52 (1992): 695–704. This article presents, explains, and defends the temporal parts solution to the problem of change. Hinchliff, Mark. 'The Puzzle of Change.' Philosophical Perspectives 10 (1996): 119–36. This article presents, explains, and defends the presentist solution to the problem of change. Wasserman, Ryan. 'The Argument from Temporary Intrinsics.' Australasian Journal of Philosophy 81 (2003): 413–19. This article presents, explains, and defends the relationist solution to the problem of change. Sider, Theodore. Four-Dimensionalism . Oxford: Oxford University Press, 2001. This book provides an introduction to various issues related to the problem of change, including the nature of time, tense, and persistence. Chapter 5 presents, explains, and defends the stage-view solution to the problem of change. Online Materials Change. URL: http://plato.stanford.edu/entries/change/ The Stanford Encyclopedia of Philosophy entry on change, by Chris Mortensen. Time. URL: http://plato.stanford.edu/entries/time/ The Stanford Encyclopedia of Philosophy entry on time, by Ned Markosian. Temporal Parts. URL: http://plato.stanford.edu/entries/temporal-parts/ The Stanford Encyclopedia of Philosophy entry on temporal parts, by Katherine Hawley. Material Constitution. URL: http://plato.stanford.edu/entries/material-constitution/ The Stanford Encyclopedia of Philosophy entry on material constitution, by Ryan Wasserman. Persistence Bibliography. URL: http://tedsider.org/teaching/pp_bibliography.pdf A bibliography on change and related issues, by Theodore Sider. Sample Syllabus Books on Syllabus Rea, Michael. Material Constitution: A Reader . Lanham: Rowman & Littlefield, 1997. Sider, Theodore. Four-Dimensionalism . Oxford: Oxford University Press, 2001. van Inwagen, P. and Zimmerman, D. 2008. Metaphysics: The Big Questions . 2nd ed. Oxford: Blackwell, 2008. Week 1: Time and Tense Four-Dimensionalism , chapters 1 and 2. Markosian, Ned. 'A Defence of Presentism.' Oxford Studies in Metaphysics, Volume 1. Ed. D. Zimmerman. Oxford: Oxford University Press, 2004: 47–82. In van Inwagen, P. and Zimmerman, D. Metaphysics: The Big Questions. 2nd ed. Oxford: Blackwell, 2008: 116-123. In van Inwagen, P. and Zimmerman, D. Metaphysics: The Big Questions. 2nd ed. Oxford: Blackwell, 2008: 124-129. Week 2: Time and Persistence Four-Dimensionalism , chapter 3. McGrath, Matthew. 'Temporal Parts.' Philosophy Compass 2 (2007): 730–48. In van Inwagen, P. and Zimmerman, D. Metaphysics: The Big Questions. 2nd ed. Oxford: Blackwell, 2008: 265-267. Hawthorne, J, Scala, M., and Wasserman, R. 'Recombination, Humean Supervenience, and Causal Constraints: An Argument for Temporal Parts?' Oxford Studies in Metaphysics , Volume 1. Ed. D. Zimmerman, Oxford: Oxford University Press, 2004: 301-318. Week 3: Change and Presentism In van Inwagen, P. and Zimmerman, D. Metaphysics: The Big Questions. 2nd ed. Oxford: Blackwell, 2008: 141-149. In van Inwagen, P. and Zimmerman, D. Metaphysics: The Big Questions. 2nd ed. Oxford: Blackwell, 2008: 267-269. In van Inwagen, P. and Zimmerman, D. Metaphysics: The Big Questions. 2nd ed. Oxford: Blackwell, 2008: 269-281. Week 4: Change and Temporal Parts Four-Dimensionalism , pp. 92–8. Heller, Mark. 'Things Change.' Philosophy and Phenomenological Research 52 (1992): 695–704. Lombard, Lawrence. 'The Doctrine of Temporal Parts and the "No Change" Objection.' Philosophy and Phenomenological Research 54 (1994): 365–72. Week 5: Change, Relationism, and Adverbialism Hawley, Katherine. 'Why Temporary Properties are not Relations between Physical Objects and Times.' Proceedings of the Aristotelian Society 98 (1998): 211–16. Wasserman, Ryan. 'The Argument from Temporary Intrinsics.' Australasian Journal of Philosophy 81 (2003): 413–19. Lewis, David. 'Tensing the Copula.' Mind 111 (2002): 1–13. Caplan, Ben. 'Why so Tense about the Copula?' Mind 114 (2007): 703–8. Week 6: Change and Tropes Ehring, Douglas. 'Lewis, Temporary Intrinsics and Momentary Tropes.' Analysis 57 (1997): 254–8. MacBride, Fraser. 'Four New Ways to Change Your Shape.' Australasian Journal of Philosophy 79 (2001): 81–9. Simons, Peter. 'On Being Spread Out in Time: Temporal Parts and the Problem of Change.' Existence and Explanation . Eds. W. Spohn, B.C. van Fraassen, and B. Skyrms. Dordrecht: Kluwer, 1991: 131-147. Weeks 7 and 8: Special Topic – Material Change Four-Dimensionalism , chapter 5. Selections from Material Constitution: A Reader. Week 9: Special Topic – Change of Position In van Inwagen, P. and Zimmerman, D. Metaphysics: The Big Questions. 2nd ed. Oxford: Blackwell, 2008: 186-195. In van Inwagen, P. and Zimmerman, D. Metaphysics: The Big Questions. 2nd ed. Oxford: Blackwell, 2008: 195-215. Week 10: Special topic – Changing the Past In van Inwagen, P. and Zimmerman, D. Metaphysics: The Big Questions. 2nd ed. Oxford: Blackwell, 2008: 224-235. van Iwagen, Peter. 'Changing the Past.' Oxford Studies in Metaphysics , Volume 5 . Ed. D. Zimmerman. Oxford: Oxford University Press, 2009: 1-22. Hudson, H. and Wasserman, R. 'Van Inwagen on Time Travel and Changing the Past.' Oxford Studies in Metaphysics , Volume 5. Ed. D. Zimmerman. Oxford: Oxford University Press, 2009: 41-49. (shrink)

In the common law world, Albert Venn Dicey is known as the high priest of orthodox constitutional theory, as an ideological and nationalistic positivist. In his analytical coldness, his celebration of sovereign power, and his incessant drive to organize and codify legal rules separate from moral values or political realities, Dicey is an uncanny figure. This book challenges this received view of Dicey. Through a re-examination of his life and his 1885 book Law of the Constitution, the high priest Dicey (...) is defrocked and a more human Dicey steps forward to offer alternative ways of reading his canonical text, who struggled to appreciate law as a form of reasoned discourse that integrates values of legality and authority through methods of ordinary legal interpretation. The result is a unique common law constitutional discourse through which assertions of sovereign power are conditioned by moral aspirations associated with the rule of law. (shrink)

Causation is one of philosophy's most venerable and thoroughly-analyzed concepts. However, the study of how ordinary people make causal judgments is a much more recent addition to the philosophical arsenal. One of the most prominent views of causal explanation, especially in the realm of harmful or potentially harmful behavior, is that unusual or counternormative events are accorded privileged status in ordinary causal explanations. This is a fundamental assumption in psychological theories of counterfactual reasoning, and has been transported to philosophy by (...) Hitchcock and Knobe (2009). A different view--the basis of the culpable control model of blame (CCM)--is that primary causal status is accorded to behaviors that arouse negative evaluative reactions, including behaviors that stem from nefarious motives, negligence or recklessness, a faulty character, or behaviors that lead to harmful or potentially harmful consequences. This paper describes four empirical studies that show consistent support for the CCM. (shrink)

Measuring gene expression on a global scale has been one of the vexing problems of cell biology. Velculescu et al.(1) recently proposed a system for identifying gene expression levels based on very short sequence tags – about nine base pairs – located at a specific site within a gene transcript. By coupling the strategy to current automated sequencing machines and the large expressed sequence tag databases, it should be possible to follow changes in gene expression for large numbers of genes (...) economically and accurately. (shrink)

Clinical bioethics is big business. There are now hundreds of people who bioethics in community and university hospitals, nursing homes, rehabilitation and home care settings, and some who play the role of clinical ethics consultant to transplant teams, managed care companies, and genetic testing firms. Still, there is as much speculation about what clinically active bioethicists actually do as there was ten years ago. Various commentators have pondered the need for training standards, credentials, exams, and malpractice insurance for ethicists engaged (...) in clinical consultation. Much of the discussion seems to accept an implicit presumption that all clinical ethics consultation practices look pretty much alike. But is this accurate? What do clinical ethicists do, how and where do they do it, and what kind of clinical ethics is useful in the hospital and in other settings? (shrink)

Corporate social responsibility (CSR) has emerged as an effective way for firms to create favorable attitudes among consumers. Although prior research has addressed the direct influence of proactive and reactive CSR on consumer responses, this research hypothesized that consumers’ perceived organizational motives (i.e., attributions) will mediate this relationship. It was also hypothesized that the source of information and location of CSR initiative will affect the motives consumers assign to a firms’ engagement in the initiative. Two experiments were conducted to test (...) these hypotheses. The results of Study 1 indicate that the nature of a CSR initiative influences consumer attribution effects and that these attributions act as mediators in helping to explain consumers’ responses to CSR. Study 2 suggests that the source of the CSR message moderates the effect of CSR on consumer attributions. The mediating influence of the attributions as well as the importance of information source suggests that proper communication of CSR can be a viable way to inculcate positive corporate associations and purchase intentions. (shrink)

We show that the fundamental legal structure of a well-written financial contract follows a state-transition logic that can be formalized mathematically as a finite-state machine (specifically, a deterministic finite automaton or DFA). The automaton defines the states that a financial relationship can be in, such as “default,” “delinquency,” “performing,” etc., and it defines an “alphabet” of events that can trigger state transitions, such as “payment arrives,” “due date passes,” etc. The core of a contract describes the rules by which different (...) sequences of events trigger particular sequences of state transitions in the relationship between the counterparties. By conceptualizing and representing the legal structure of a contract in this way, we expose it to a range of powerful tools and results from the theory of computation. These allow, for example, automated reasoning to determine whether a contract is internally coherent and whether it is complete relative to a particular event alphabet. We illustrate the process by representing a simple loan agreement as an automaton. (shrink)

An Argument From Evolutionary Naturalism An Argument from Personal Dignity References.

The rapid, recent emergence of new medical knowledge models has engendered a dizzying number of new medical initiatives, programs and approaches. Fields such as evidence-based medicine and translational medicine all promise a renewed relationship between knowledge and medicine. The question for philosophy and other fields has been whether these new models actually achieve their promises to bring about better kinds of medical knowledge—a question that compels scholars to analyze each model’s epistemic claims. Yet, these analyses may miss critical components that (...) explain how these models actually work and function. Using the case of translational medicine, this paper suggests that analyses which treat these models as a primarily epistemic interventions miss the way that new approaches are increasingly shaped by specific financial and commercial agendas. Ultimately, social epistemological analyses that are attentive to market forces are required to make sense of emerging bioscientific research models, which are increasingly tethered to or a manifestation of increasingly financialized models of science research and innovation. (shrink)

Since Freud, clinicians have understood that disturbing memories contribute to psychopathology and that new emotional experiences contribute to therapeutic change. Yet, controversy remains about what is truly essential to bring about psychotherapeutic change. Mounting evidence from empirical studies suggests that emotional arousal is a key ingredient in therapeutic change in many modalities. In addition, memory seems to play an important role but there is a lack of consensus on the role of understanding what happened in the past in bringing about (...) therapeutic change. The core idea of this paper is that therapeutic change in a variety of modalities, including behavioral therapy, cognitive-behavioral therapy, emotion-focused therapy, and psychodynamic psychotherapy, results from the updating of prior emotional memories through a process of reconsolidation that incorporates new emotional experiences. We present an integrated memory model with three interactive components – autobiographical (event) memories, semantic structures, and emotional responses – supported by emerging evidence from cognitive neuroscience on implicit and explicit emotion, implicit and explicit memory, emotion-memory interactions, memory reconsolidation, and the relationship between autobiographical and semantic memory. We propose that the essential ingredients of therapeutic change include: (1) reactivating old memories; (2) engaging in new emotional experiences that are incorporated into these reactivated memories via the process of reconsolidation; and (3) reinforcing the integrated memory structure by practicing a new way of behaving and experiencing the world in a variety of contexts. The implications of this new, neurobiologically grounded synthesis for research, clinical practice, and teaching are discussed. (shrink)

American orthodox medicine consolidated its professional authority in the early 20th Century on the basis of its unbiased scientific method. The centerpiece of such a method is a strategy for identifying truly effective new therapies, i.e., the randomized clinical trial (RCT). A crucial component of the RCT in illnesses without established treatment is the placebo control. Placebo effects must be identified and distinguished from pharmacological effects because placebos produce actual but unexplained therapeutic successes. The blinding necessary for a proper placebo-controlled (...) RCT therefore introduces an epistemic bias into orthodox medicine: therapeutic successes that rely upon a direct link between knowing and healing, such as placebo effects, are discarded in favor of therapeutic successes that rely upon an indirect link between knowing and healing, such as pharmacological interventions. Where the capacity to produce therapeutic results once validated the method of clinical medical science, now method validates results. The clinical consequences of this method of testing therapies include a diminished vision of the therapeutic potential of the doctor-patient relationship and of the potential human resources available for healing. Keywords: doctor-patient relationship, epistemology, placebo effect, professionalization, randomized clinical trials CiteULike Connotea Del.icio.us What's this? (shrink)

If libertarianism is true, then there is a sense in which agents have it within their power to bring it about that some world is actual. Against recent arguments for the incompatibility of divine foreknowledge and human freedom, I offer an account of power over the past which takes this implication of libertarianism into consideration. I argue that the resulting account is available to Ockhamists and that it is immune to recent criticisms of the notion of counterfactual power over the (...) past. But I contend that it is not an option for Molinists and that this fact leaves that position vulnerable to incompatibilist arguments. (shrink)

Lonergan is commonly read, sometimes favorably and sometimes unfavorably, through a Thomist lens. But the evidence suggests that Lonergan was interested in Hegel before he undertook his studies of Aquinas and that his interest in Hegel persisted throughout his intellectual career. Lonergan regarded Hegel’s absolute idealism as “the halfway house” on the way to his own critical realist position. His effort to establish his critical realism was informed and guided by a struggle with Hegel’s absolute idealist response to Kant’s Critical (...) Philosophy. Lonergan scholars who hope to understand adequately Lonergan’s critical realist position would do well to give more serious attention to his early and perduring relationship to Hegel. (shrink)

For more than 20 years, both here and abroad, significant efforts have been undertaken to provide equal access to nutritional food for all citizens. Yet, the numbers of under-nourished continue to rise, as do those afflicted with non-communicable diseases (NCDs) such as obesity, diabetes, hypertension, and heart disease. Clearly, current efforts are not working. Relying on the psychological phenomena of learned helplessness and fundamental attribution error, it is argued that certain individuals may not be willing, or able, to take actions (...) that are currently prescribed regarding access to nutritious food. The water is muddied regarding potential solutions as the various actors involved (e.g., corporations, governments, individuals) cannot agree on a starting point and continue to point fingers regarding responsibility. It is posited that emphasis needs to shift from the current “one-size-fits-all” approach to one that is more tailored to the various actors, specifically the individuals. Within the group of individuals (consumers), based on Wenar’s Least Cost Theory, even further distinction must be made between those who see themselves as capable actors and those who do not. In this conceptual piece intended to refocus the discussion surrounding food access, we propose that future research should approach these issues from a unit of analysis perspective in an attempt to identify the solutions most likely to succeed at various participating levels. (shrink)

During periods of scarcity, or the fear of it, many health systems create or adopt triage protocols to determine how to best allocate limited resources. Interest in such protocols has become acute...

In "Behavioral Law and Economics: The Assault on Consent, Will, and Dignity," Mark D. White uses the moral philosophy of Immanuel Kant to examine the intersection of economics, psychology, and law known as "behavioral law and economics." Scholars in this relatively new field claim that, because of various cognitive biases and failures, people often make choices that are not in their own interests. The policy implications of this are that public and private organizations, such as the state and employers, (...) can and should design the presentation of options and default choices in order to "steer" people to the decision they would make, were they able to make choices in the absence of their cognitive biases and failures. Such policies are promoted under the name "libertarian paternalism," because choice is not blocked or co-opted, but simply "nudged." White argues that such manipulation of choice is impossible to conduct in people's true interests, and any other goal pursed by policymakers substitutes their own ends, however benevolent they may be, for people's true ends. Normatively, such manipulation should not be conducted because it fails to respect the dignity and autonomy of persons, what some hold to be the central idea in Kant's ethical system, and which serves to protect the individual from coercion, however subtle, from other persons or the state. (shrink)

Is it rational to strive for the unattainable? In this short and provocative study, Nicholas Rescher vigorously defends both the rationality and practicality of seriously pursuing impossible dreams.

I argue in this article that there is a mistake in Searle's Chinese room argument that has not received sufficient attention. The mistake stems from Searle's use of the Church-Turing thesis. Searle assumes that the Church-Turing thesis licences the assumption that the Chinese room can run any program. I argue that it does not, and that this assumption is false. A number of possible objections are considered and rejected. My conclusion is that it is consistent with Searle's argument to hold (...) onto the claim that understanding consists in the running of a program. (shrink)

Mandating psychiatric evaluation for patients who request physician‐assisted suicide may not offer the clearcut protection from possible coercion or other abuse that proponents assert. Competence itself is a complex concept and determinations of decisionmaking capacity are not straightforward, nor is the relationship between mental illness and decisionmaking capacity in dying patients clearly understood. And casting psychiatrists as gatekeepers in end‐of‐life decisions poses risks to the profession itself.

This book explores the complex issue of international ethics in the two dominant schools of thought in international relations; Liberalism and Realism. Both theories suffer from an inability to integrate the ethical and pragmatic dimensions of foreign policy. Liberal policy makers often suffer from moral blindness and a tendency toward coercion in the international arena, whilst realists tend to be epistemic sceptics, incorporating Nietzsche’s thought, directly or indirectly, into their theories. Mark Gismondi seeks to resolve the issues in these (...) two approaches by adopting a covenant based approach, as described by Daniel Elazar’s work on the covenant tradition in politics, to international relations theory. The covenant approach has three essential principles: policy makers must have a sense of realism about the existence of evil and its political consequences power must be shared and limited liberty requires a basis in shared values. _Ethics, Realism and Liberalism in International Relations_ will be of interest to students and researchers of politics, philosophy, ethics and international relations. (shrink)

Applied Natural Science: Environmental Issues and Global Perspectives will provide the reader with a complete insight into the natural-scientific pattern of the world, covering the most important historical stages of the development of various areas of science, methods of natural-scientific research, general scientific and philosophical concepts, and the fundamental laws of nature. The book analyzes the main scientific trends and developments of modern natural science and also discusses important aspects of environmental protection. Topics include: the problem of "the two cultures": (...) the mathematization of natural sciences and the informatization of society; the non-linear nature of the processes occurring in nature and society; application of the second law of thermodynamics to describe the development of biological systems; global problems of the biosphere; theory and practice of stable organic paramagnetic materials; polymers and the natural environment. Key features include: an interdisciplinary approach in considering scientific and technical problems; a discussion of general scientific trends in modern natural science, including globalization challenges in nature and society, the organic chemistry of stable paramagnetic materials, the fundamentals of the environmental chemistry of polymeric materials, etc.; a justification of applying classical (non-equilibrium) thermodynamics to studying the behavior of open (including biological) systems. (shrink)